Welcome to the "Children of 1997" Birth Cohort Study!

We are a large, population-representative, Chinese birth cohort in Hong Kong, which was established in 1997, based on all births in April and May 1997. Our birth cohort is the largest such study in Asia to date.

Hong Kong provides a novel setting for a birth cohort, because Hong Kong has all the advantages of a modern post-industrial environment, with a high standard of living, a stable population, universal access to health care and the infrastructure to support such a study. However, Hong Kong’s population has undergone an unusually recent and rapid economic/epidemiologic transition over the last 60 years, because the population of Hong Kong was largely formed by migration in the mid 20th century from essentially pre-industrial conditions in China. This setting provides a unique opportunity to examine the developmental origins of health in the context of the epidemiologic transition over only two or three generations. Much of developing Asia has since followed Hong Kong’s developmental trajectory. Insights from the “Children of 1997” birth cohort study may predict the future epidemiologic changes and inform public health responses in the rest of Asia.

NEWS

MASS FOLLOW UP

We have launched a new round of follow-up in August 2013. At this follow-up, we will be conducting various health assessments, including lung function tests, body fat percentage tests, and collection of biomaterials (such as saliva, urine, hair and nails). Blood tests will also be done to test for fasting glucose, lipids, liver and renal function, and complete blood count. Participants will also complete questionnaires on their health and lifestyle. As a token of our appreciation, we will offer supermarket coupons to participants who have completed the assessments. Each participant will also receive a detailed report on all the assessment results. We will use the data collected to study the risk factors for common chronic diseases such as diabetes and heart disease. Through this study, we hope to establish a "biobank" with the collected biomaterials for future research use.

We have set up three study sites in Tuen Mun, Yau Ma Tei and North Point for the convenience of all “Children of 1997” members. So far, over 2000 cohort members have already attended our follow-up! We do value each of your participation, as every one of you are unique members of this long-term study. By joining our follow-up, you can know more about your own health as well as support public health research in Hong Kong.

We would like to invite you to take part in our Biobank Project. If you have not received an invitation letter, please be patient, and you will hear from us soon. Meanwhile, if you have any questions, free to contact us via email at aprmay97@hku.hk or by phone at 39176781. We look forward to seeing you!

Blood Taking
Blood Pressure Measurement
Lung Function Measurement
Head Circumference Measurement
Hair Collection
Questionnaire Completion
 
 

About Us

Background

Most people in Hong Kong remember 1997 to be a significant year because of the handover of Hong Kong back to the People's Republic of China from the former British colonial power. However, for a small group of researchers from The University of Hong Kong and the Department of Health, Hong Kong Special Administrative Region, 1997 was the year that one of Asia's largest birth cohorts was established. 

Given the smoking epidemic in China and the strong presence in the field of tobacco control of the department of Community Medicine (predecessor of the School of Public Health) at the Faculty of Medicine, the study was originally designed to provide high quality evidence concerning the impact of second hand smoking on infant health.
This study is funded by the Health Care and Promotion Fund of Hong Kong launched the birth cohort. 

 

 

Special thanks to Dr. Cindy Lin and Ms. Florence Tsang

 
 
Newsletter 2016

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Newsletter 2015

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Newsletter 2014

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Newsletter 2013 (Winter)

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Newsletter 2012

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Newsletter 2007 (Spring)

Journal Publications

The following is the list of published research findings our ‘Children of 1997’ research team has published in international journals.

Cheng TS, Kwok MK, Leung GM, Schooling CM. The Associations of Breast Feeding with Infant Growth and Body Mass Index to 16 years: 'Children of 1997'. Paediatr Perinat Epidemiol. 2017 Dec 27. doi: 10.1111/ppe.12434. [pubmed]

 

- Huang JV, Leung GM, Schooling CM. The Association of Air Pollution With Pubertal Development: Evidence From Hong Kong's “Children of 1997” Birth Cohort. American journal of epidemiology. 2017 May 15;185(10):914-23 [pubmed]

- Kwok MK, Leung GM, Schooling CM. Pubertal testis volume, age at pubertal onset, and adolescent blood pressure: Evidence from Hong Kong's “Children of 1997” birth cohort. American Journal of Human Biology. 2017 Mar 1. [pubmed]

- Kwok MK, Leung GM, Schooling CM. Glucose-6-Phosphate Dehydrogenase Deficiency and physical and mental health until adolescence. PLoS One. 2016 Nov; 11(11): e0166192 [pubmed]

- Huang JV, Leung GM, Schooling CM. The association of air pollution with birthweight and gestational age: evidence from Hong Kong's "Children of 1997" birth cohort. Journal of Public Health. 2016 Jul [pubmed]

- Lai TC, Leung GM, Schooling CM. Maternal age of menarche and blood pressure in adolescence: Evidence from Hong Kong's "Children of 1997" Birth Cohort. PLoS One. 2016 Jul; 11(7): e0159855 [pubmed]

- Kwok MK, Schooling CM, Subramanian SV, Leung GM, Kawachi I. Pathways from parental educational attainment to adolescent blood pressure. Journal of Hypertension. 2016 Sep; 34(9): 1787-95 [pubmed]

- Kwok MK, Schooling CM, Leung GM, Subramanian SV. Grandparental education, parental education and adolescent blood pressure. Preventive Medicine. 2016 Sep; 90: 59-65 [pubmed]

- Wang H, Lin SL, Leung GM, Schooling CM. Age at onset of puberty and adolescent depression: "Children of 1997" Birth Cohort. Pediatrics. 2016 Jun; 137(6). pii:e20153231 [pubmed]

- Leung JY, Leung GM, Schooling CM. Socioeconomic disparities in preterm birth and birth weight in a non-Western developed setting: evidence from Hong Kong "Children of 1997" birth cohort. Journal of Epidemiology and Community Health. 2016 Nov; 70(11): 1074-1081 [pubmed]

- Kwok MK, Leung GM, Schooling CM. Association of birth order with early adolescent growth, pubertal onset, blood pressure and size: Evidence from Hong Kong's "Children of 1997" Birth Cohort. PLoS One. 2016 Apr; 11(4): e0153787 [pubmed]

- Lai TC, Au Yeung SL, Lin SL, Leung GM, Schooling CM. Maternal age of menarche and adiposity: Evidence from Hong Kong's "Children of 1997" birth cohort. Epidemiology. 2016 May; 27(3); 433-7 [pubmed]

- Leung JY, Lam HS, Leung GM, Schooling CM. Gestational age, birth weight for gestational age, and childhood hospitalizations for asthma and other wheezing disorders. Pediatric and Perinatal Epidemiology. 2016 Mar; 30(2): 149-59 [pubmed]

- Hui LL, Leung GM, Schooling CM. Social patterning in adiposity in adolescence. Prospective observations from the Chinese Birth Cohort "Children of 1997". PLoS One. 2016 Jan; 11(1): e0146198 [pubmed]

- Leung JY, Kwok MK, Leung GM, Schooling CM. Breastfeeding and childhood hospitalization for asthma and other wheezing disorders. Annals of Epidemiology. 2016 Jan; 26(1): 21-7 [pubmed]

- Kwok MK, Subramanian SV, Leung GM, Schooling CM. Household income and adolescent blood pressure in a Chinese birth cohort: "Children of 1997". Social Science and Medicine. 2015 Nov; 144: 88-95 [pubmed]

- Hui LL, Lam HS, Leung GM, Schooling CM. Late prematurity and adiposity in adolescents: Evidence from "Children of 1997" birth cohort. Obesity (Sliver Spring). 2015 Nov; 23(11): 2309-14 [pubmed]

- Leung CY, Leung GM, Schooling CM. Early second-hand smoke exposure and child and adolescent mental health: evidence from Hong Kong's "Children of 1997" birth cohort. Addiction. 2015 Nov; 110(11): 1811-24 [pubmed]

- Hui LL, Wong MY, Leung GM, Schooling CM. The association of infant growth patterns with adiposity in adolescence: Prospective observations from Hong Kong's "Children of 1997" Birth Cohort. Pediatric and Perinatal Epidemiology. 2015 Jul; 29(4): 326-34 [pubmed]

- Wang H, Leung GM, Lam HS, Schooling CM. Gestational age and adolescent mental health: evidence from Hong Kong's "Children of 1997" birth cohort. Archives of disease in childhood. 2015 Jun; 100(9): 856-62 [pubmed]

- Leung JY, Li AM, Leung GM, Schooling CM. Mode of delivery and childhood hospitalizations for asthma and other wheezing disorders. Clinical & Experimental Allergy. 2015 Jun; 45(6):1109-17 [pubmed]

- Wang H, Leung GM, Schooling CM. Adiposity and early adolescent emotional/behavioural problems. Journal of Pediatrics. 2015 Jun; 166(6):1404-9 [pubmed]

- Leung CY, Leung GM, Schooling CM. Informal child care and adolescent psychological well-being: Hong Kong's "Children of 1997" birth cohort. PLoS One. 2015 Mar; 10(3):e0120116 [pubmed]

- Wang H, Leung GM, Schooling CM. Life course body mass index and adolescent self-esteem: Evidence from Hong Kong's "Children of 1997" Birth Cohort. Obesity (Silver Spring). 2015 Feb; 23(2): 429-35 [pubmed]

- Wang H, Leung GM, Schooling CM. Life course adiposity and adolescent depressive symptoms among Hong Kong adolescents. Journal of Adolescent Health. 2014 Sep;55(3):408-14. [pubmed]

- Tarrant M, Schooling CM, Leung SL, Mak KH, Ho LM, Leung GM. Impact of breastfeeding on infectious disease hospitalisation: the children of 1997 cohort. Hong Kong Medical Journal. 2014 Aug;20 Suppl 4:5-6.[pubmed]

- Leung CY, Leung GM, Schooling CM. Migrant status and child and adolescent psychological well-being: evidence from Hong Kong's 'Children of 1997' birth cohort. Journal of Epidemiology & Community Health. 2014 Oct 10. pii: jech-2014-204429 [pubmed]

- Kwok MK, Au Yeung SL1, Leung GM1, Schooling CM. Birth weight, infant growth, and adolescent blood pressure using twin status as an instrumental variable in a Chinese birth cohort: "Children of 1997".Annals of Epidemiology. 2014 Jul;24(7):509-15. [pubmed]

- Hou WW, Tse MA, Lam TH, Leung GM, Schooling CM. Adolescent testosterone, muscle mass and glucose metabolism: evidence from the 'Children of 1997' birth cohort in Hong Kong. Diabetic Medicine. 2014 Oct 11.[pubmed]

- Lin SL, Leung GM, Lam TH, Schooling CM. Timing of solid food introduction and obesity: Hong Kong's "children of 1997" birth cohort.Pediatrics. 2013 May;131(5):e1459-67.[pubmed]

- Lin SL, Leung GM, Schooling CM. Mode of delivery and adiposity: Hong Kong's "Children of 1997" birth cohort. Annals of Epidemiology. 2013 Nov;23(11):693-9. [pubmed]

- Kwok MK, Leung GM, Lam TH, Leung SS, Schooling CM. Grandparental education, parental education and child height: evidence from Hong Kong's "Children of 1997" birth cohort. Annals of Epidemiology. 2013 Aug;23(8):475-84.[pubmed]

- Kwok MK, Freeman G, Lin SL, Lam TH, Schooling CM. Simulated growth trajectories and blood pressure in adolescence: Hong Kong's Chinese Birth Cohort. Journal of Hypertension. 2013 Sep;31(9):1785-97.[pubmed]

- Kwok MK, Leung GM, Schooling CM. Breastfeeding and adolescent blood pressure: evidence from Hong Kong's "Children of 1997" Birth Cohort. American Journal of Epidemiology. 2013 Sep 15;178(6):928-36.[pubmed]

- Kwok MK, Leung GM, Schooling CM. Breast feeding and early adolescent behaviour, self-esteem and depression: Hong Kong's 'Children of 1997' birth cohort. Archives of Disease in Childhood. 2013 Nov;98(11):887-94. [pubmed]

- Heys M, Lin SL, Lam TH, Leung GM, Schooling CM. Lifetime growth and blood pressure in adolescence: Hong Kong's "Children of 1997" birth cohort. Pediatrics. 2013 Jan;131(1):e62-72. [pubmed]

- Schooling CM, Hui LL, Ho LM, Lam TH, Leung GM. Cohort profile: 'children of 1997': a Hong Kong Chinese birth cohort. International Journal of Epidemiology. 2012 Jun;41(3):611-20. [pubmed]

- Lin SL, Tarrant M, Hui LL, Kwok MK, Lam TH, Leung GM, Schooling CM. The role of dairy products and milk in adolescent obesity: evidence from Hong Kong's "Children of 1997" birth cohort. PLoS One.2012;7(12):e52575. [pubmed]

- Lin SL, Lee SL, Hui LL, Au Yeung SL, Tse MA, Leung GM, Schooling CM. Pubertal muscle mass and diabetes markers in Chinese adolescents.American Journal of Human Biology. 2012 Mar-Apr;24(2):183-5.[pubmed]

- Kwok MK, Leung GM, Lam TH, Schooling CM. Breastfeeding, childhood milk consumption, and onset of puberty. Pediatrics. 2012 Sep;130(3):e631-9. [pubmed]

- Hui LL, Leung GM, Wong MY, Lam TH, Schooling CM. Small for gestational age and age at puberty: evidence from Hong Kong's "Children of 1997" birth cohort. American Journal of Epidemiology. 2012 Nov 1;176(9):785-93. [pubmed]

- Hui LL, Leung GM, Lam TH, Schooling CM. Inter-generational influences on age at onset of puberty: Hong Kong's 'Children of 1997' birth cohort.International Journal of Epidemiology. 2012 Feb;41(1):292-300.[pubmed]

- Hui LL, Wong MY, Lam TH, Leung GM, Schooling CM. Infant growth and onset of puberty: prospective observations from Hong Kong's "Children of 1997" birth cohort. Annals of Epidemiology. 2012 Jan;22(1):43-50.[pubmed]

- Hui LL, Leung GM, Lam TH, Schooling CM. Premature birth and age at onset of puberty. Epidemiology. 2012 May;23(3):415-22. [pubmed]

- Schooling CM, Kwok MK, Yau C, Cowling BJ, Lam TH, Leung GM. Spatial proximity and childhood hospital admissions in a densely populated conurbation: evidence from Hong Kong's 'Children of 1997' birth cohort.Health Place. 2011 Sep;17(5):1038-43. [pubmed]

- Lin SL, Leung GM, Hui LL, Lam TH, Schooling CM. Is informal child care associated with childhood obesity? Evidence from Hong Kong's "Children of 1997" birth cohort. International Journal of Epidemiology.2011 Oct;40(5):1238-46. [pubmed]

- Kwok MK, Leung GM, Lam TH, Schooling CM. Early life infections and onset of puberty: evidence from Hong Kong's children of 1997 birth cohort. Epidemiology. 2010 Nov;21(6):847-54. [pubmed]

- Tarrant M, Kwok MK, Lam TH, Leung GM, Schooling CM. Breast-feeding and childhood hospitalizations for infections. Epidemiology. 2010 Nov;21(6):847-54. [pubmed]

- Schooling CM, Yau C, Cowling BJ, Lam TH, Leung GM. Socio-economic disparities of childhood Body Mass Index in a newly developed population: evidence from Hong Kong's 'Children of 1997' birth cohort.Archives of Disease in Childhood. 2010 Jun;95(6):437-43. [pubmed]

- Kwok MK, Schooling CM, Lam TH, Leung GM. Paternal smoking and childhood overweight: evidence from the Hong Kong "Children of 1997".Pediatrics. 2010 Jul;126(1):e46-56. [pubmed]

- Kwok MK, Schooling CM, Lam TH, Leung GM. Does breastfeeding protect against childhood overweight? Hong Kong's 'Children of 1997' birth cohort. International Journal of Epidemiology. 2010 Feb;39(1):297-305.[pubmed]

- Hui LL, Schooling CM, Wong MY, Ho LM, Lam TH, Leung GM. Infant growth during the first year of life and subsequent hospitalization to 8 years of age. Epidemiology. 2010 May;21(3):332-9. [pubmed]

- Hui LL, Leung GM, Cowling BJ, Lam TH, Schooling CM. Determinants of infant growth: Evidence from Hong Kong's "Children of 1997" birth cohort.Annals of Epidemiology. 2010 Nov;20(11):827-35. [pubmed]

- Mak YW, Loke AY, Abdullah AS, Lam TH. Household smoking practices of parents with young children, and predictors of poor household smoking practices. Public Health. 2008 Nov;122(11):1199-209. [pubmed]

- Kwok MK, Schooling CM, Ho LM, Leung SS, Mak KH, McGhee SM, Lam TH, Leung GM. Early life second hand smoke exposure and serious infectious morbidity during the first eight years: evidence from Hong Kong's "Children of 1997" birth cohort. Tobacco Control.  2008. [pubmed]

- Hui LL, Schooling CM, Leung SSL, Mak KH, Ho LM, Lam TH, Leung GM. Birth Weight, Infant Growth and Childhood Body Mass Index Hong Kong’s Children of 1997 Birth Cohort.  Archives of Disease in Childhood.2008; 162(3):212-218. [pubmed]

- Hui LL, Schooling CM, Cowling BJ, Leung SSL, Lam TH, Leung GM. Are universal standards for optimal infant growth appropriate? Evidence from a Hong Kong Chinese birth cohort. Archives of Disease in  Childhood.Archives of Disease in Childhood. 2008 Jul;93(7):561-5. [pubmed]

- Leung GM, Ho LM, Tin KY, Schooling CM, Lam TH. Health care consequences of caesarean birth during the first 18 months of life.Epidemiology. 2007 Jul; 18(4):479-84. [pubmed]

- Leung GM, Lam TH, Ho LM, Lau YL. Health consequences of breastfeeding: doctors’ visits and hospitalisations during the first 18 months of life in Hong Kong Chinese infants.  Epidemiology. 2005; 16:328-35.[pubmed]

- Leung GM, Ho LM, Lam TH. Second-hand smoke exposure, smoking hygiene, and hospitalization in the first 18 months of life.  Archives of Paediatrics and Adolescent Medicine. 2004; 158:687-93. [pubmed]

- Leung GM, Ho LM, Lam TH. The economic burden of environmental tobacco smoke in the first year of life.  Archives of Disease in Childhood.2003; 88:767-71. [pubmed]

- Leung GM, Lam TH, Ho LM. Breast-feeding and its relation to smoking and mode of delivery.  Obstetrics and Gynaecology. 2002; 99:785-94.[pubmed]

- Leung GM, Ho LM, Lam TH. Breastfeeding rates in Hong Kong: a comparison of the 1987 and 1997 birth cohorts.  Birth. 2002; 29:162-8.[pubmed]

- Lam TH, Leung GM, Ho LM. The effects of environmental tobacco smoke on health services utilization in the first 18 months of life.   Pediatrics.2001 Jun;107(6):E91. [pubmed]

 
 

Papers in Progress

The following is the list of published research findings our ‘Children of 1997’ research team has published in international journals.

 

- Cheng TS, Leung GM, Lai LH, Leung JYY, Kwok MK, Au Yeung SL, Schooling CM. Growth from birth to puberty and glycaemic indicators at ~17 Years: evidence from Hong Kong’s “Children of 1997” birth cohort

 

- Cheng TS, Leung GM, Lai LH, Leung JYY, Kwok MK, Au Yeung SL, Schooling CM. Growth from birth to puberty and blood pressure and lipid profile at ~17 years: evidence from Hong Kong’s “Children of 1997” birth cohort

 

Funding

Over the years, our team has received funding from various bodies. Below is a list of grants that have been awarded for the "Children of 1997" birth cohort studies.

Grants: 

- Health and Medical Research Fund, 2012 (Grant No. 10111491), Hong Kong SAR, China.

- Health and Medical Research Fund, 2012 (Grant No. 10111311), Hong Kong SAR, China.

- Health and Medical Research Fund, 2012 (Grant No. 10111201), Hong Kong SAR, China.

- RGC General Research Fund 2011  (Grant No. 769811), Hong Kong SAR, China.

- Health and Health Services Research Fund, 2011 (Grant No. 09101061), Hong Kong SAR, China.

- Health and Health Services Research Fund, 2010 (Grant No. 0809076), Hong Kong SAR, China.

- Health and Health Services Research Fund, 2008 (Grant No. 05060671), Hong Kong SAR, China.

- The University of Hong Kong, University Research Council Strategic Theme of Public Health. 2007.

- Research Fund for the Control of Infectious Diseases, 2007 (Grant No. 006060592), Hong Kong SAR, China.

- Research Fund for the Control of Infectious Diseases, 2006 (Grant No. 04050172), Hong Kong SAR, China.

- Health and Health Services Research Fund, 2005 (Grant No. 03040771), Hong Kong SAR, China.

- World Health Organization funding the 1987 Birth Cohort in the collaborative study with the "Children of 1997" Birth Cohort.

- Hong Kong Health Care and Promotion Fund 1996 (Grant No. 216106), Hong Kong SAR, China.

 

Events

December 2012 - Movie Appreciation & Tram Party

November 2012 - Hong Kong Children’s Symphony Orchestra Winter Concert

February 2010   - HKU Campus Tour

April/May 2008  - Happy Birthday to the Lovely Children of 1997!

January 2008    - RTHK's Top Ten Chinese Gold Songs

December 2007 - Merry Christmas to all!

April/May 2007  - Logo Design Competition

Movie Appreciation
Tram Party
 

Media Coverage

14-Jun-2015  - 「九七的兒女」為公共衞生出力 (Chinese Version Only)

22-Sep-2014  - "Children of 1997" mentioned in Hong Kong Connection (RTHK). (Chinese Version Only)

18-July-2014  - "Children of 1997" Cohort Study Press Release - Breastfeeding’s Impact on Hong Kong’s Public Health.

06-Nov-2007   - "Children of 1997" to feature in TVB evening show.

29-May-2007   - Birth Cohort holds press conference

 
 
FAQs

In this section, we will answer questions and comments that we have received from our cohort as well as others who are interested in our study. We hope you find these questions and answers helpful and informative.

Please let us know if you encounter any problems or have any suggestions. To send a comment, go to our CONTACT US page.

 

1. What is a birth cohort?

A birth cohort study tracks a group forward in time from birth onwards. Birth cohort studies provide a unique epidemiological tool for understanding how biological, socio-economic or behavioural factors throughout life may influence health.

Most existing birth cohorts are based on populations of European descent. However, the recent re-discovery of non-Mendelian heritable changes in gene expression driven by the environment in previous generations, (i.e. epigenetics), has drawn attention to the need for life time study of populations with different histories of economic development.

 

2. Is the information that I contribute to the research kept confidential?

The research team here at The University of Hong Kong take privacy and confidentiality very seriously. Information is kept in password protected computer files only accessible to university staff in the research team. This information is not available to any other persons outside of the research team.

 

3. Is there any oversight of the research process?

Before the launch of any projects based on the birth cohort, ethical approval is sought from the appropriate bodies, including The University of Hong Kong-Hospital Authority Hong Kong West Cluster Joint Institutional Review Board and the Ethics Committee of the Department of Health, Government of the Hong Kong SAR, People's Republic of China. Analysis is always performed anonymously to ensure privacy.

 

4. If I have a question about my child's health, can I contact the research team?

Although we may not be able to answer personally all the medical queries that you may have, you are welcome to call our office and share with our research staff your concerns about your child. We will then see how we can help you, based on your individual needs.

 

5. Are there any other birth cohort studies similar to the "Children of 1997" study?

There are currently several other birth cohorts around the world like the "Children of 1997" Birth Cohort Study. If you are interested in what discoveries other birth cohort studies have made, below are links to other on-going birth cohorts.

Avon Longitudinal Study

National Birth Cohort Studies (1946, 1958, 1970 and Millenium cohorts)

Children of the 1950s

Northern Finland Birth Cohorts (NFBC)

Cebu Longitudinal Health and Nutrition Survey

 

-- If you have any other questions, please call our research staff at (852) 3917 6781. --

「九七的兒女」 出生隊列研究小組

 Children of 1997 Birth Cohort Study Team

地址 Address:

 

香港薄扶林沙宣道七號白文信樓一樓香港大學公共衞生學院 

九七的兒女」 出生隊列研究小組

“Children of 1997” Birth Cohort Study, School of Public Health,

The University of Hong Kong, 1/F, Patrick Manson Building,

7 Sassoon Road, Hong Kong.

電話 Telephone:  (852) 3917 6824

傳真 Fax: (852) 3520 1945 

電郵 Email: aprmay97@hku.hk

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